American College of Cardiology Foundation

11/18/2019 | Press release | Distributed by Public on 11/18/2019 06:34

MedPage Today | AHA 2019

AHA 2019 | Philadephia, PA

November 17, 2019
Post-ISCHEMIA: Focus Turns to Testing for Stable Angina
PHILADELPHIA - After the ISCHEMIA trial delivered its clear determination that early revascularization isn't better than medication alone for moderate-to-severe, but stable, heart disease, cardiologists saw little 'reperfusion injury' for their practice overall.

November 17, 2019
Entresto Data Support Wider Reach of 'Fifth Pillar' HF Drug
PHILADELPHIA - The benefits of angiotensin receptor-neprilysin inhibition (ARNI) therapy extend beyond heart failure (HF) with reduced ejection fraction (HFrEF), according to investigators revisiting the PARAGON-HF and PARADIGM-HF trials.

November 17, 2019
Even in ACS, Early Aspirin Withdrawal Promising Post-PCI
PHILADELPHIA - High-risk patients benefited from the withdrawal of aspirin from dual antiplatelet therapy (DAPT) a few months after stenting for non-ST-segment elevation acute coronary syndrome (ACS), a TWILIGHT substudy confirmed.

November 17, 2019
TAVR Valve Type Can Mean the Difference in PVR, Death Risk
PHILADELPHIA - Operators shouldn't expect the same results from transcatheter aortic valve replacement (TAVR) using balloon-expandable versus self-expanding devices, a French registry study suggested.

November 17, 2019
Apabetalone Falls Short in Patients with T2D and ACS
PHILADELPHIA - Investigational apabetalone was not better than placebo on a background of optimal medical therapy for reducing adverse cardiovascular (CV) outcomes in patients with type 2 diabetes and recent acute coronary syndrome (ACS), researchers reported here.

November 16, 2019
GALILEO: Little Clues for Why Xarelto Failed After TAVR
PHILADELPHIA - Patients were harmed when given rivaroxaban (Xarelto) to prevent valve surface thromboembolism after transcatheter aortic valve replacement (TAVR) if they had no established indication for it, according to the phase III trial GALILEO.

November 16, 2019
ISCHEMIA: Early Invasive Tx on Par with Meds for Stable CAD
PHILADELPHIA - It's COURAGE all over again: the landmark ISCHEMIA trial failed to show an outcome benefit from adding early stenting or bypass surgery to optimal medication in patients with stable, moderate-to-severe ischemic heart disease in the contemporary era.

November 16, 2019
ORION-10: siRNA Tx Halves LDL in Atherosclerotic CVD
PHILADELPHIA - The investigational drug inclisiran can further halve LDL cholesterol in patients with atherosclerotic cardiovascular disease (ASCVD) already on lipid-lowering therapies, according to the ORION-10 trial presented here.

November 16, 2019
AHA: HF Benefit of Dapagliflozin Affirmed in Non-Diabetics
PHILADELPHIA - Heart failure patients with reduced ejection fraction but no diabetes appear to benefit significantly when the diabetes drug dapagliflozin (Farxiga) is added to their treatment regimens, researchers reported here.

November 16, 2019
AHA Dedicates $20 Million to Youth Vaping Research
PHILADELPHIA - The American Heart Association (AHA) declared a multi-million dollar war on the electronic cigarette industry, and use of e-cigarettes by youth.

November 16, 2019
Colchicine Scores for Secondary Prevention After MI
PHILADELPHIA - A low oral dose of gout medication colchicine reduced ischemic events in heart attack survivors, the COLCOT trial showed, further affirming the inflammatory hypothesis.

November 14, 2019
All Eyes on ISCHEMIA Trial at AHA
PHILADELPHIA - A landmark trial pitting early revascularization against contemporary medical therapy in stable ischemic heart disease promises to set the halls abuzz at the upcoming American Heart Association (AHA) meeting here.

November 12, 2019
Vaping Worse for Heart Than Cigarettes?
PHILADELPHIA - E-cigarette smokers were worse off than conventional cigarette smokers in terms of coronary microvascular vascular function, researchers found in a small study.

Keywords:AHA Annual Scientific Sessions, AHA19

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