12/03/2021 | News release | Distributed by Public on 12/03/2021 04:38
Healthcare-associated infections (HAIs), also referred to as "nosocomial" or "hospital" infections, are infections acquired while hospitalized, and generally occur 48 hours after admittance. HAIs also include occupational infections among clinical staff. These infections can be transmitted in all types of clinical settings and can spread to a patient host by various means. Most HAIs ascribe to common bacteria, fungal, and viral pathogens. Due to frequent usages of antibiotics within hospitals, types of bacteria and their resistance to antibiotics are distinct from those external to the hospital. Thus, complications caused by HAIs can be severe, particularly in patients with chronic illnesses, who are immunocompromised, young children and older people.
The most common infection sites include surgical sites, the urinary tract, and the lungs. Depending on the type of HAI, the attributed pathogen and the severity of illness, clinical manifestations may vary and encompass:
The most common types of HAIs include:
The medical term for this type of infection is septicemia. It comes into being when an infection in any part of the body enters the bloodstream and spreads to other parts of the body. Septicemia can be potentially fatal and should be treated promptly. Catheter-related bloodstream infections (CRBSI) are common in a clinical setting.
Ventilator-associated pneumonia is a lung infection that develops in a person who is on a ventilator. A ventilator is a machine used to help a patient breathe by giving oxygen through a tube placed in a patient's mouth, nose, or through a hole in the front of the neck. An infection may occur if pathogens enter through the tube and get into the patient's lungs.
UTIs are common infections most often caused by bacteria. UTI happens when bacteria, often from the skin or rectum, enter the urethra and infect the urinary tract. It can affect several parts of the urinary tract, but the most common type is a bladder infection (cystitis).
Kidney infection (pyelonephritis) is another type of UTI. They're less common but more serious than bladder infections.
A surgical site infection is an infection that occurs after surgery in the part of the body where the surgery took place. Surgical site infections can sometimes be superficial infections involving the skin only. Other surgical site infections are more severe and can involve tissues under the skin, organs, or implanted material. SSI is one of the most common types of infection in the operating room.
Other signs and symptoms may include abdominal pain, distention, cramping, fever, nausea, anorexia, and dehydration.
Various things in a hospital environment can cause nosocomial infections.
Antibiotics: Various hospital-associated infections may ascribe to the most critical antibiotic-resistant (AR) pathogens. Antibiotics often are prescribed to prevent or alleviate an existing infectious condition while a patient is in the hospital. Many types of bacteria in the body of a patient are healthy and eliminate harmful bacteria. Since antibiotics kill both healthy and unhealthy bacteria, taking them can increase the chances of nosocomial infection.
Urinary catheters: Urinary catheters are tubes inserted through your urethra into the bladder of a patient. It is often used during surgeries or other treatments when a patient cannot get up to use the bathroom for a long time. Leaving one inserted for too long can cause a bacterial urinary tract infection.
Mechanical Ventilation: Pathogens can live inside a ventilator and enter the body of a patient.
Central Venous Catheters: A central line is a tube that connects to a patient's neck, chest, arm, or groin to deliver medicine straight into the bloodstream. Pathogens can pass through the tube and cause dangerous bloodstream infections. These pathogens can live on medical gloves, on the skin, where the tube is inserted, or on the external end of the tube.
Surgical Procedures: Surgical site infections occur when harmful pathogens enter the body of a patient when the skin, hair, or surgical tools are not completely clean before surgery.
These pathogens are responsible for central line-associated bloodstream infections (CLABSI), catheter-associated urinary tract infections (CAUTI), surgical site infections (SSI), ventilator-associated pneumonia (VAP), and many other such infections.
The detrimental adversity resulting from HAIs comes at a high cost for patients and their families. Not only do HAIs extend the duration of hospital stays, they also cause chronic disability, harmfully fortifying antimicrobial resistance, creating massive financial burden for health systems, patients and their families. HAIs overall account for approximately 37,000 deaths or more in Europe each year, and they are responsible for about 99,000 deaths in the USA.
The economic impacts of HAIs differ for patients, health care providers, third-party payers, and society in general. The annual costs of the most common types of HAI occurring in acute care hospitals are estimated to be approximately $10 billion in US adult inpatient populations alone. Listed in the following order, the most high-priced HAI area along with the respective contributing percentages are Skin and Soft Tissue Infection (33.7%); Ventilator-Associated Pneumonia (31.7%), Central Line-Associated Blood Stream Infection (18.9%), Clostridioides difficile Infection (15.4%) and Catheter-Associated Urinary tract Infection (0.3%).
The CDC estimates that all HAIs cost the US healthcare system from $28 billion to $45 billion annually. In Europe, HAI-associated costs are approximately €7 billion annually.
Hand hygiene plays a crucial role in preventing skin pathogen transmission. Washing hands thoroughly with soap and using alcohol-based hand sanitizer is a significant part of infection control and isolation precautions. Studies have shown that following hand hygiene recommendations reduces the pathogen load, prevents transmission of HAIs.
Personal protective equipment (PPE) such as gloves, gowns, masks, and eye protection to protect from contacting blood and body fluids is also necessary to prevent airborne, droplet, and contact transmission.
In addition, hospital waste potentially can cause HAIs. Therefore, monitoring and enforcing sanitation protocols and appropriate cleaning regimens are recommended to ensure proper handling of medical equipment and disposal of single-use items.
To effectively reduce antimicrobial resistance in a HAI prevention program, it will not be enough to just examine and monitor antimicrobial use. We should also implement adequate infection control measures and integrated laboratory, surveillance, and administrative supports. Although the best possible strategy for controlling antibiotic-resistant organisms is different from one healthcare facility to another, the Infection Control and Prevention Plan and epidemiology professionals at each facility are valuable resources to provide educational programs and to implement targeted infection control measures, which include the use of quality PPE, hand hygiene resources, patient placement and isolation. With committed organizational support and expert recommendations adopted into daily practice routines, the morbidity and mortality attributed to HAIs should be under control.
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