Prospectus Certification by Investment Company (Form 497J)

Global X Funds

605 Third Avenue, 43rd Fl

New York, NY 10158

January 18, 2022

VIA EDGAR

U.S. Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

Re: Global X Funds ("Trust")

File Nos. 333-151713, 811-22209

Ladies and Gentlemen:

On behalf of Global X Funds (the "Registrant") and pursuant to Rule 497(j) under the Securities Act of 1933, as amended (the "Securities Act"), I hereby certify that (i) the prospectus and statement of additional information for the series of Global X Funds contained in Post-Effective Amendment No. 663 to the Registrant's Registration Statement on Form N-1A (the "Amendment"), filed on January 14, 2022 and effective January 15, 2022, which would have been filed pursuant to Rule 497(c) under the Securities Act, would not have differed from the prospectus and statement of additional information contained in the Amendment, and (ii) the text of the Amendment was filed electronically with the Securities and Exchange Commission on January 14, 2022, accession number 0001432353-22-000009.

Please do not hesitate to call me at (646) 716-3239 if you have any questions regarding the foregoing. Thank you for your attention to this matter.

Sincerely,

/s/ Susan Lively

Susan Lively