Prospectus Certification by Investment Company (Form 497J)

State Street Institutional Investment Trust

One Iron Street

Boston, MA 02210

October 20, 2021

VIA EDGAR

Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

File Nos.: 811-09819 and 333-30810

Dear Sir or Madam:

Pursuant to Rule 497(j) under the Securities Act of 1933, as amended (the "1933 Act"), we are transmitting for filing via EDGAR on behalf of the Trust this letter as certification that the Prospectuses and Statements of Additional Information, each dated October 15, 2021, do not differ from those contained in the Post-Effective Amendment No. 287 to the Trust's Registration Statement on Form N-1A that was filed electronically via EDGAR on October 15, 2021 (Accession #0001193125-21-298955).

If you have any questions, please contact me at (617) 662-8420.